Know your enemy: HIV-1 reservoir in the spotlight
HIV-1 forms a reservoir that persists despite prolonged therapy and is considered the main barrier to an HIV cure. Various methods to measure HIV-1 reservoir in infected individuals have been developed, but the field is still searching for better ways. The recent review collection in Retrovirology “Measuring HIV-1 persistence in vivo”, edited by Dr. Alexander Pasternak and Prof. Ben Berkhout, summarizes our current understanding of HIV-1 persistence and tools to measure it.