‘Big data’ in clinical trials could have the potenital to transform real-world evidence in medicine and healthcare. A new review published today in Trials refelects on the promises, barriers, and implications of this and here, co-authors Lars Hemkens and Kimberly Mc Cord discuss some of the issues and what’s next for clarifying uncertainties.
Monthly Archives: January 2018
A new year brings a new series for Blood Cancer Journal, an open-access journal published by Springer Nature. January 2018 sees the launch of a new article type called ‘Current Treatment Algorithms’. In this blog, Dr Ayalew Tefferi and Dr S. Vincent Rajkumar introduce the concept of this new article type and discuss its relevance in the vast field of hematological cancers.
Simulated scenarios are a vital component in the training of health professionals. Debriefing is seen as a vital part of this learning process, but do students also learn as they engage in scenario-based simulations? Research recently published in Advances in Simulation seems to suggest that they do.
Despite the increasing effectiveness of breast cancer treatments over the last 50 years, tumors often become resistent to the drugs used. While drug combinations could be part of the solution to this problem, their development is very challenging. In this blog post Jorge Zanudo explains how it is possible to combine physical and mathemathical models with clinical and biological data to determine which drug combinations would be most effective in breast cancer therapy.
Huntington’s disease is a rare, inherited neurodegenerative disorder that progressively impairs motor and cognitive functions. It was previously thought that exercise might act as a stressor, accelerating disease progression; but now increased knowledge of the underlying mechanisms of the disease has led to new research suggesting that endurance exercise may actually have therapeutic potential for rare diseases like Huntington’s.