A large epigenome-wide association study published today in BMC Medicine provides the evidence that childhood obesity is triggered by specific factors occurring before birth, such as mother’s lifestyle, and fetal genetic and epigenetic characteristics. Here, author Neerja Karnani summarizes these findings.
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Systematic reviews (SRs) and meta-analyses (MAs) of clinical trial results are regarded as the highest level of medical evidence to establish the effectiveness and safety of interventions in a comprehensive, transparent, and reproducible nature. Unfortunately, evidence shows that not all SRs and trials are guaranteed to have been performed with the necessary methodological rigor. A study published today in Systematic Reviews reports on evidence of incomplete child-centric reporting details. Here the authors tell us more.