Altered
glucose metabolism of tumor cells was first noted by Otto Warburg in the
1920s. In later years, the discovery of
oncogenes and tumor suppressor genes transformed our understanding of cancer, but
left metabolism neglected. Now recent advances show that many oncogenes drive
cancer by altering metabolic pathways, leading to an explosion of research. It is also clear that metabolic diseases,
such as diabetes and obesity, are linked to cancer in ways that are not entirely
clear.

Cancer & Metabolism is a new
interdisciplinary journal launched at the crossroads of these disciplines. The journal is edited by pioneering clinician
scientists Chi Van Dang, University of Pennsylvania, USA, and Michael Pollak,
McGill University, Canada. Chi Van Dang
is director of the Abramson Cancer Centre and established the first mechanistic
link between the Myc oncogene and
cellular energy metabolism. Michael
Pollak leads a research group at the Lady Davis Institute, which demonstrated a
role for insulin and insulin-like growth factors in cancer biology, research
that led to the development of new drugs.

Professor Dang commented that “It has become self-evident
that metabolism and bioenergetics are regulated by cancer genes. Cancer & Metabolism is launched
uniquely to fulfil the needs of a burgeoning field.” Professor
Pollak added that “The scope of Cancer & Metabolism will allow for an interdisciplinary
readership including cancer biologists, endocrinologists, oncologists, clinical
trialists and population scientists.”

Cancer &
Metabolism welcomes studies on molecular
biology and genetics; whole-body metabolism, including diabetes and obesity, in
relation to cancer; cancer metabolomics and metabolism-based imaging. The journal accepts basic research as well as
preclinical and clinical studies of metabolism-related cancer therapies.

You are warmly invited to join in the success of this
journal by submitting your next research article for
publication. For more information, please visit the journal website or
contact the Editorial Office.